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Random Library

Random library is an indispensable tool for sequence optimization. It has the ability to generate alternative peptides that could have the potential for enhanced activity. We substitute selected residues randomly and simultaneously with all other 20 natural amino acids via a shotgun approach. Our random library fabricates as many variations as possible within the selected amino acid residues.

Overlapping Peptide		Alanine Scanning

Truncation Library		Positional Scanning

Random Library		Scrambled Library

References

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Irving MB, Pan O, and Scott JK. Random-peptide libraries and antigen-fragment libraries for epitope mapping and the development of vaccines and diagnostics. Curr. Opin. Chem. Biol. Jun 2001; 5(3): 314-24.
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