Mutagenesis Outsourcing Services
| Mutagenesis
is a fundamentally important DNA manipulation technique. It involves changing the base sequence of the DNA molecule, usually for the purposes of testing the effect of this change on gene or DNA function. Site-directed mutagenesis, one of the most frequently-used mutations, is an invaluable technique
in the study of protein structure-function relationships, gene
expression, and vector modification.
Most site-directed mutagenesis is based on the PCR
method, in which strand separation is accomplished by using a
denaturing step to separate the complementary strands and in which
efficient polymerization of the PCR primers is possible. In theory, the
PCR method can be performed in the lab, but it requires considerable
optimization, necessitates a staff skilled in both PCR and primer
design. Often, the time and energy poured into in-lab PCR mutagenesis
would be better spent elsewhere, such as on the lab's core creative
work.
By outsourcing in vitro mutagenesis projects to GenScript your lab can profit from an extremely short turnaround time, even in demanding mutagenesis
projects. At GenScript, we guarantee top accuracy and unlimited sites.
Moreover, we offer comprehensive upstream and downstream services,
including template sequencing, expression vector construction, and
protein expression and purification. The proven expertise of
GenScript's team in the field of in vitro mutagenesis combined
with our optimized technology allows us to deliver mutated and verified
vectors (purified DNA and bacterial clones) within only a few days,
thereby saving scientists’ valuable time.
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Quotations and Ordering:
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For quotation requests and questions, you may contact us by phone, email, fax, or via our secured online quotation system.
Orders can be placed by phone, email, fax, or online with a formal PO (Purchase Order) or credit card.
Please send your samples with full shipping information and PO number (if applicable) with a hard copy of the completed Mutagenesis Quotation Request Form to Mutagenesis Service, GenScript USA Inc., 860 Centennial Ave., Piscataway, NJ 08854, US.
Our customer service representatives are available 24 hours Monday through Friday.
You may contact us anytime for assistance.
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